Minnesota Urolith Center
Cats with Kidney Stones and/or Chronic Kidney Disease
Dr. Jody Lulich at the Minnesota Urolith Center (MUC) is investigating the connection between kidney stones and chronic kidney failure in cats. Help us solve this common, costly and devastating problem. We need whole, formalin-fixed kidneys of cats with nephroliths or chronic kidney disease. If cats have a kidney removed during therapy, succumb to their illness, or are humanely euthanized; place whole, intact kidneys (after carefully removing the outer capsule) in formalin. We’ll cover shipping; please email Dr. Jody Lulich at email@example.com.
One of the most compassionate acts we can perform as veterinarians and cat owners is to contribute to the efforts of scientists working to cure diseases.
Genetic Risk Factors for Dogs with Urinary Stones
Calcium Oxalate Uroliths
Hereditary Xanthine Uroliths
Tests for these mutations are available: http://z.umn.edu/xanthinuria. Dachshund and Chihuahua dogs with a history of xanthine stones may be eligible for free testing.
Contact Dr. Furrow at firstname.lastname@example.org for more information about either study or other genetic stone types.
Cystinuric Dogs and Cats
The Minnesota Urolith Center, in collaboration with The Section of Medical Genetics at the University of Pennsylvania's School of Veterinary Medicine are working together to identify cystinuric dogs and cats. Recently, UPenn identified an androgen-dependent type of cystinuria and SLC3A1 and SLC7A9 mutations in autosomal recessive or dominant cystinuric dogs and cats. The goal is to further characterize the molecular and metabolic genetic components associated with cystine urolith formation in dogs and cats.
The data obtained from each animal is important. The Minnesota Urolith Center received over 71,000 canine uroliths in 2015. Only 2.4% were composed of cystine; and very few uroliths were from the breeds listed above. Cystinuria is even less common in cats. Approximately 0.1% of feline uroliths received at the Minnesota Urolith Center in 2015 were composed of cystine.
Recruiting cystinuric cats of all breeds.
Recruiting cystinuric dogs of Irish Terrier, Kromfohrlaender, and Scottish Terrier Breeds
Contact email@example.com for more information.