Clinical Investigation Center

Current Clinical Trials

We have many opportunities for pet animals to participate in clinical trials. Each listing below has a quick summary plus a link to more information for each study.

Clinical Trials Seeking Participants

Cancer (Oncology)

Cancer (Oncology)

Dogs with hemangiosarcoma, other splenic lesions, other cancers and healthy young dogs - Shine On

Multi-phase study to develop effective methods for early detection and for prevention of canine hemangiosarcoma. 

Learn more about the Shine On Project

VIGOR trial: Translational approach for development of a novel oncolytic immunotherapy for osteosarcoma

Dogs diagnosed with osteosarcoma of a limb for a placebo-controlled, blinded study of a new therapy given in the hospital, followed by amputation and chemotherapy

Learn more about the VIGOR trial

Dogs with hemangiosarcoma (HSA) - autologous vaccine

Dogs diagnosed with hemangiosarcoma of the spleen or liver scheduled for surgery at the VMC (splenectomy or lobectomy) for a clinical trial of an autologous vaccine (made from the dog's own tumor cells) CURRENTLY ON HOLD.

Learn more about Autologous vaccine for immunotherapy of hemangiosarcoma

Dogs and Cats having tumors removed at the VMC

We are studying intraoperative lavage cytology which is routinely use in human surgical oncology to aid in post-surgical planning for patients. Dogs and cats having tumors of the thorax, abdomen or mammaries removed at the VMC may be eligible.

Learn more about ILC as a predictive indicator of tumor margins

Brain tumor trials

Dogs with solitary brain tumors with MRI diagnosis of glioma or meningioma for a twelve month trial at the Veterinary Medical Center.  

Learn more about Canine Brain Tumor Clinical Trials

Animal Cancer Care and Research

Learn more about the Animal Cancer Care and Research program

Dermatology

Internal Medicine

Internal Medicine

Cats with chronic diarrhea or constipation

Study seeking cats 1 year old or more for an 8-week clinical trial to evaluate the use of a cat food to help control chronic diarrhea or constipation. Read more about Feline FACTS study.

Miniature Schnauzer, Bichon Frise, Shih Tzu, Border Collie and Dachshund dogs 

Study seeking these breeds with a history of calcium oxalate stones or dogs > 9 years old which have never had calcium oxalate stones

Read more about Novel mutations associated with calcium oxalate urolithiasis risk in dogs

Orthopedics/ Surgery

Orthopedics/ Surgery

Cats with osteoarthritis

Study of an investigational veterinary product to treat clinical signs of osteoarthritis in a blinded, placebo-controlled, 3-month clinical trial. Learn more about Feline OA study.

Dogs with osteoarthritis (OA) in elbow or knee

We are studying biomarkers in synovial fluid (joint fluid) and activity levels of dogs with OA before and after an anti-inflammatory medication is taken. Dogs with lameness due to OA and one leg worse than the others may be eligible for this 42 day study. Learn more about synovial fluid and activity study for dogs with osteoarthritis.

Dogs with luxating patellas in both knees

We are studying a new surgical technique for correcting this condition which could be more precise, decrease pain and increase mobility. Learn more about surgical technique for dogs with medial patellar luxation. 

Dogs and Cats having tumors removed at the VMC

We are studying intraoperative lavage cytology which is routinely use in human surgical oncology to aid in post-surgical planning for patients. Dogs and cats having tumors of the thorax, abdomen or mammaries removed at the VMC may be eligible. Learn more about ILC as a predictive indicator of tumor margins.

Dogs having minimally invasive (laparoscopic) surgery

Study of effects of insufflation (filling the abdomen wiht CO2 gas) on particular cardiovascular systems: a prospective, randomized clinical trial. Learn more about Minimally invasive surgery monitoring.