Pamela J. Skinner, PhD

Pamela J. Skinner

Contact Info

skinn002@umn.edu

Mailing Address:
205G Veterinary Science Building
1971 Commonwealth Ave.
St. Paul, MN, 55108

PhD, University of Minnesota, 1998

BS, University of Minnesota

Summary

Expertise

HIV and prion diseases

Research

Research Summary/Interests

My research program focuses on understanding HIV and prion disease immunopathogenesis and the development of novel treatments for these diseases. Recently we found that HIV- and SIV-specific cytotoxic lymphocytes are largely excluded from B cell follicles where virus is most concentrated, supporting the hypothesis that B cell follicles are an immune privileged site that allows ongoing viral replication. We are working to develop cellular immunotherapy to target HIV-specific CTL to B cell follicles to functionally cure HIV. In addition, I also study gene expression changes that occur during prion disease to gain insights into disease pathogenesis and develop novel assays to diagnose prion disease.

Publications

Teaching

Courses

VBS1001: Introduction to Biotechnology, Coordinator