Jianming Wu, DVM, PhD

Jianming Wu

Contact Info

jmwu@umn.edu

Office Phone 612-624-1768

Fax 612-625-0204

Lab Phone 612-625-0517

Mailing Address:
235B AS/VM Building
1988 Fitch Avenue
Saint Paul, MN 55108

Postdoctoral fellow, Immunology/Genetics, Cornell University Medical Center

Postdoctoral fellow, Immunology/Genetics, University of Alabama at Birmingham

PhD, Molecular, Cellular, and Developmental Biology, Iowa State University

DVM, Yangzhou University

MS, Preventive Veterinary Medicine, Yangzhou University

Summary

Genetics and Genomics cluster

Expertise

Functional genomics of human immunoglobulin Fc receptors; Genetics of human autoimmune diseases.

Research

Research Summary/Interests

I am interested in the functional genomics of human IgG Fc receptors (Fc?Rs) and human inflammatory diseases. Functional genetic variants of Fc?Rs significantly influence the pathogenesis of autoimmune inflammatory diseases such as cancer and autoimmune diseases. We also study genetic mechanisms of human neutrophil antigen (HNA) formation and their role human diseases. Human neutrophil antigen 2 (HNA-2) deficiency is a common phenotype as 3-5% humans do not express HNA-2. HNA-2 deficient individuals are prone to produce HNA-2 alloantibodies that cause a number of disorders including transfusion-related acute lung injury and immune neutropenia.

Publications

Teaching

Academic Interests and Focus

Immunology, genetics, molecular and cellular biology, mechanisms of human inflammatory diseases.

Courses

CMB8202 Mechanisms of animal health and diseases

CVM6906 Critical Scientific Reading