Jennifer Granick, DVM, MS, PhD, Diplomate ACVIM (SAIM)

Assistant Professor, Department of Veterinary Clinical Sciences

Jennifer Granick

Contact Info

Assistant Professor, Department of Veterinary Clinical Sciences

College of Veterinary Medicine


PhD, University of California, Davis, 2012

DVM, University of Wisconsin, 2003

MS, University of Minnesota, 2008

BS, Northland College, 1998

Summary

Awards & Recognition

  • 2011-2013 NIH T32 Trainee, Animal Models of Infectious Disease (PI, Solnick)
  • 2011 Society of Leukocyte Biology Presidential Award, 2nd Place
  • 2009-2011 University of California, Davis Graduate Group in Comparative Pathology Block Grant Award
  • 2010 Scholar Award, Philanthropic Education Organization
  • 2008-2010 Floyd and Mary Schwall Fellowship in Medical Research
  • 2007 Minnesota Veterinary Medical Association James O. Hansen Continuing Education Award
  • 2003 Rock Valley Veterinary Medical Association Award
  • 2001 University of Wisconsin School of Veterinary Medicine Summer
  • Research Fellowship
  • 2000 Phi Zeta Veterinary Honor Society

Professional Associations

  • Diplomate, American College of Veterinary Internal Medicine (Small Animal Internal Medicine), 2008
  • American Veterinary Medical Association
  • International Society of Companion Animal Infectious Disease

Research

Research Summary/Interests

My research focuses globally on infectious disease and host immune response. I am specifically interested in the role of white blood cell precursors (hematopoietic stem and progenitor cells) outside of their bone marrow niche in response to infection. I study a model of Staphylococcus aureus skin wound infection and how these stem and progenitor cells participate in the innate immune response, specifically 1)mechanisms of differentiation to mature immune cells within the wound environment, 2)trafficking of these cells to sites of infection outside the bone marrow, and 3)how these cells influence the response of other immune cells in the wound. A technical area of expertise is multiparameter flow cytometry.

Research Funding Grants

“Endogenous Hematopoietic Stem and Progenitor Cell Function at the Site of Cutaneous Staphylococcus aureus Infection“- University of Minnesota Grant-in-Aid of Research, Artistry and Scholarship, Principal Investigator, 1/1/2014-6/30/2015

Publications

  1. Carrade Holt, DD, JA Wood, JL Granick, NJ Walker, KC Clark, and DL Borjesson. (2014) Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source. Stem Cells and Development. June 1;23(11):1258-65.
  2. Kim, MH, F Gorouhi, S Ramirez, JL Granick, A Soulika, SI Simon, and RR Isseroff. (2014). Catecholamine stress alters neutrophil trafficking and impairs wound healing by ß2 adrenergic receptor mediated upregulation of IL-6. J. Investig. Dermatology. March; 134(3):809-17.
  3. Granick JL, PC Falahee, D Dahmubed, DL Borjesson, LS Miller, SI Simon. (2013). Staphylococcus aureus signaling through TLR2 and MyD88 is required for enhanced trafficking to and myeloid differentiation in infected wounds. Blood. Sept. 5; 122(10):1170-1778.
  4. CA Toupadakis, JL Granick, M Sagy, A Wong, E Ghassemi, DJ Chung, DL Borjesson2, CE Yellowley. (2013). Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model. Cytotherapy. Sept; 15(9): 1136-1147.
  5. EJ Armstrong, JL Granick, SI Simon. (2013). Editorial: A missing link? Monocyte activation by uremic toxins in cardiorenal syndrome. J Leukocyte Biology. June; 93:821-23.
  6. Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, Granick JL, Matsushima H, Takashima A, Iwakura Y, Cheung AL, Cheng G, Lee DJ, Simon SI, Miller LS. (2012). Neutrophil-derived IL-1? is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice. PLoS Pathogens. Nov;8(11):e1003047.
  7. Granick JL, SI Simon, DL Borjesson. (2012). Hematopoietic stem and progenitor cells as effectors in innate immunity. Bone Marrow Research. 2012:165107.
  8. Kim, MH*, JL Granick*, C Kwok, NJ Walker, DL Borjesson, FR Curry, L Miller, SI Simon. (2011). Neutrophil survival and c-kit+ progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood. March; 117(12):3343-3352 *shared first authorship
  9. Granick JL, PJ Armstrong, JB Bender. (2009). Anaplasma phagocytophilum infection in dogs: 34 cases (2000-2007). J Am Vet Med Assoc. Jun 15;234(12):1559-65.
  10. Granick, JL, PJ Armstrong. (2009). Make your diagnosis: Diarrhea and vomiting in a Shiba Inu. Clinician’s Brief. March. www.cliniciansbrief.com.
  11. Granick JL, DV Reneer, JA Carylon, DL Borjesson. (2008). Anaplasma phagocytophilum infects cells of the megakaryocytic lineage through sialylated ligands but fails to alter platelet production . J Medical Microbiology. Apr;57:416-23.

Teaching

Teaching Areas

My primary teaching responsibilities are in small animal infectious diseases, problems based medicine and clinical instruction.

Clinical

Board Certifications

Diplomate ACVIM (SAIM)

Clinical Interests

My clinical interests are in infectious diseases that affect cats and dogs, particularly those that also affect humans, and antimicrobial stewardship.