Hinh Ly, MA, PhD

Hinh Ly

Contact Info

hly@umn.edu

Mailing Address:
295 AS/VM Building
1988 Fitch Avenue
Saint Paul, MN 55108

PhD, University of North Carolina at Chapel Hill

MA, University of California, Los Angeles

BS, University of California, Los Angeles

Summary

Expertise

Molecular Virology, Innate Immunity, Host-Pathogen Interactions

Research

Research Summary/Interests

Lassa fever virus infection can lead to severe and sometime fatal hemorrhagic fever diseases in humans, for which there is no vaccine or effective drug. Studies of Lassa (LASV) and other pathogenic arenaviruses have been hindered by the strict requirement for BSL-4 containment to work with these select agents. We have developed an infectious molecular clone for a prototypic BSL2 arenavirus (Pichinde virus) as well as a safe and convenient surrogate animal model for LASV. These novel systems have afforded us with unique resources and unprecedented opportunities to investigate in details the processes of viral entry/infection, genome replication/transcription and virulence. We are also interested in characterizing novel mechanisms of host innate-immune suppression by these viruses. 

Publications

Teaching

Courses

  • CMB 8303 – Comparative Models of Disease – course coordinator and instructor
  • VMED 5410 – Scientific Writing and Speaking – course instructor